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991.
Perceptions of sensation and pain in healthy people are believed to be the net result of sensory input and descending modulation from brainstem and cortical regions depending on emotional and cognitive factors. Here, the influence of attention on neural activity in the spinal cord during thermal sensory stimulation of the hand was investigated with functional magnetic resonance imaging by systematically varying the participants' attention focus across and within repeated studies. Attention states included (1) attention to the stimulus by rating the sensation and (2) attention away from the stimulus by performing various mental tasks of watching a movie and identifying characters, detecting the direction of coherently moving dots within a randomly moving visual field and answering mentally-challenging questions. Functional MRI results spanning the cervical spinal cord and brainstem consistently demonstrated that the attention state had a significant influence on the activity detected in the cervical spinal cord, as well as in brainstem regions involved with the descending analgesia system. These findings have important implications for the detection and study of pain, and improved characterization of the effects of injury or disease. 相似文献
992.
Takeshi Yoshizako Akihiko WadaKoji Uchida Shinji HaraMikio Igawa Hajime KitagakiStephan E. Maier 《Magnetic resonance imaging》2011,29(1):106-110
Purpose
This retrospective study was designed to evaluate the apparent diffusion coefficient (ADC) of line scan diffusion images (LSDI) in normal prostate and prostate cancer. Single-shot echo planner images (SS-EPI) were used for comparison.Materials and Methods
Twenty prostate tumors were examined by conventional MRI in 14 patients prior to radical prostatectomy. All patients were examined with a 1.5-T MR imager (Signa CV/i ver. 9.1 GE Medical System Milwaukee, WI, USA). Diffusion-weighted MR imaging (DWI) using LSDI was performed with a pelvic phased-array coil, with b values of 5 and 800 s/mm2. DWI using SS-EPI was performed with a body coil, with b values of 0 and 800 s/mm2. The ADCs of each sequence for 14 normal prostate and 20 prostate cancers were histopathologically assessed. Signal-to-noise ratio (SNR) on DWI was estimated and compared for each sequence.Results
The mean ADCs (±S.D.) of normal peripheral zones (PZ), transition zones (TZ) and cancer (in 10−3 mm2/s) that used LSDI were 1.42±0.12, 1.23±0.10 and 0.79±0.19, respectively. Those that used SS-EPI were 1.76±0.26, 1.38±0.20 and 1.05±0.27, respectively. Using unpaired t test (P<.05), we found a significant difference in each sequence between normal tissue (both PZ and TZ) and the cancer. Paired t test (P<.05) also registered a significant difference between LSDI and SS-EPI. Mean SNR for DWI using LSDI was 16.49±5.03, while the DWI using SS-EPI was 18.85±9.26. The difference between the SNR of each sequence was not statistically significant by paired t test.Conclusion
We found that ADCs using LSDI and SS-EPI showed similar tendencies in the same patients. However, in all regions, LSDI ADCs had smaller standard deviations than SS-EPI ADCs. 相似文献993.
Huang J Wang AM Shetty A Maitz AH Yan D Doyle D Richey K Park S Pieper DR Chen PY Grills IS 《Magnetic resonance imaging》2011,29(7):993-1001
Objective
To determine the accuracy of magnetic resonance spectroscopy (MRS), perfusion MR imaging (MRP), or volume modeling in distinguishing tumor progression from radiation injury following radiotherapy for brain metastasis.Methods
Twenty-six patients with 33 intra-axial metastatic lesions who underwent MRS (n=41) with or without MRP (n=32) after cranial irradiation were retrospectively studied. The final diagnosis was based on histopathology (n=4) or magnetic resonance imaging (MRI) follow-up with clinical correlation (n=29). Cho/Cr (choline/creatinine), Cho/NAA (choline/N-acetylaspartate), Cho/nCho (choline/contralateral normal brain choline) ratios were retrospectively calculated for the multi-voxel MRS. Relative cerebral blood volume (rCBV), relative peak height (rPH) and percentage of signal-intensity recovery (PSR) were also retrospectively derived for the MRPs. Tumor volumes were determined using manual segmentation method and analyzed using different volume progression modeling. Different ratios or models were tested and plotted on the receiver operating characteristic curve (ROC), with their performances quantified as area under the ROC curve (AUC). MRI follow-up time was calculated from the date of initial radiotherapy until the last MRI or the last MRI before surgical diagnosis.Results
Median MRI follow-up was 16 months (range: 2-33). Thirty percent of lesions (n=10) were determined to be radiation injury; 70% (n=23) were determined to be tumor progression. For the MRS, Cho/nCho had the best performance (AUC of 0.612), and Cho/nCho >1.2 had 33% sensitivity and 100% specificity in predicting tumor progression. For the MRP, rCBV had the best performance (AUC of 0.802), and rCBV >2 had 56% sensitivity and 100% specificity. The best volume model was percent increase (AUC of 0.891); 65% tumor volume increase had 100% sensitivity and 80% specificity.Conclusion
Cho/nCho of MRS, rCBV of MRP, and percent increase of MRI volume modeling provide the best discrimination of intra-axial metastatic tumor progression from radiation injury for their respective modalities. Cho/nCho and rCBV appear to have high specificities but low sensitivities. In contrast, percent volume increase of 65% can be a highly sensitive and moderately specific predictor for tumor progression after radiotherapy. Future incorporation of 65% volume increase as a pretest selection criterion may compensate for the low sensitivities of MRS and MRP. 相似文献994.
995.
996.
997.
D. Yarımpabuç H.I. Tarman C. Yıldırım 《Mathematical Methods in the Applied Sciences》2014,37(18):2962-2971
The effect of an inclined homogeneous magnetic field on thermal convection between rigid plates heated from below under the influence of gravity is numerically simulated in a computational domain with periodic horizontal extent. The numerical technique is based on solenoidal (divergence‐free) basis functions satisfying the boundary conditions for both the velocity and the induced magnetic field. Thus, the divergence‐free conditions for both velocity and magnetic field are satisfied exactly. The expansion bases for the thermal field are also constructed to satisfy the boundary conditions. The governing partial differential equations are reduced to a system of ordinary differential equations under Galerkin projection and subsequently integrated in time numerically. The projection is performed by using a dual solenoidal bases set such that the pressure term is eliminated in the process. The quasi‐steady relationship between the velocity and the induced magnetic field corresponding to the liquid metals or melts is used to generate the solenoidal bases for the magnetic field from those for the velocity field. The technique is validated in the linear case for both oblique and vertical case by reproducing the marginal stability curves for varying Chandrasekhar number. Some numerical simulations are performed for either case in the nonlinear regime for Prandtl numbers Pr = 0.05 and Pr = 0.1. Copyright © 2014 John Wiley & Sons, Ltd. 相似文献
998.
借助于基片下方放置的磁铁,在溅射的放电空间中引入了纵向的梯度磁场,辉光放电时,其外貌发生了显著的收缩,由此沉积的薄膜在平面内存在明显的厚度梯度,用磁场中带电粒子的运动理论解释了此种薄膜的形成机制。 相似文献
999.
This paper concerns the conditional global regularity of incompressible MHD equations with horizontal dissipation and horizontal magnetic diffusion in two dimension. When only horizontal dissipation and horizontal magnetic diffusion are present, there is no control on the vertical derivatives of velocity field and magnetic field, which is the main difficulty to establish the global regularity. In this paper, we establish a global regularity criterion in terms of one entry of the velocity gradient tensor or one entry of the magnetic field gradient tensor, which extends the recent work (Fan and Ozawa, 2014). 相似文献
1000.
K. D. Singh 《Zeitschrift für Angewandte Mathematik und Physik (ZAMP)》2004,55(5):894-902
A three dimensional steady fully developed MHD Couette flow of a viscous incompressible electrically conducting fluid is analysed. The lower stationary porous plate is subjected to a periodic injection velocity and the upper porous plate in uniform motion to a constant suction velocity. A magnetic field of uniform strength applied normal to the planes of the plates is fixed with the moving plate. Neglecting the induced magnetic field, an approximate solution for the flow field is obtained and discussed with the help of graphs. 相似文献